ZEISS Axioscan 7 Spatial Biology Revolutionizes Clinical Research with Scalable Workflow Automation

(IN BRIEF) ZEISS has launched the Axioscan 7 spatial biology, a high-performance slide scanner designed for clinical research applications in spatial biology. The system supports high-throughput, automated imaging for multiplex immunofluorescence (mIF) assays, providing researchers with faster, more efficient, and reproducible results. The solution integrates AI-powered image analysis and offers compatibility with a wide range of assays. With the ability to scan up to 100 slides per run, the Axioscan 7 enhances scalability for large-volume research, supporting drug development and biomarker discovery in clinical trials.

(PRESS RELEASE) JENA, 25-Apr-2025 — /EuropaWire/ — ZEISS has officially launched the Axioscan 7 spatial biology, a high-performance slide scanner optimized for fluorescence and brightfield imaging, specifically designed for the fast-growing field of spatial biology in clinical research. This advanced solution provides an automated, high-throughput workflow, from sample staining to result reports, supporting the challenges of drug development, translational research, and clinical biomarker discovery.

Spatial biology enables researchers to explore cellular interactions within their native tissue environments, significantly enhancing the understanding of diseases and therapies, particularly in immuno-oncology. As spatial biology transitions from basic research to routine clinical applications, ZEISS responds to the increasing demand with a robust, scalable solution for high-throughput laboratories in contract research organizations (CROs), pharmaceutical companies, and biotechnology firms.

“ZEISS has extensive experience in providing reliable, high-quality solutions for demanding research environments,” says Dr. Michael Albiez, Head of ZEISS Research Microscopy Solutions. “With the Axioscan 7 spatial biology, we deliver an end-to-end workflow for high-throughput applications, combining automation, standardization, and AI-powered image analysis to enable spatial biology at scale.”

Key features of the new Axioscan 7 spatial biology include:

• Multiplex Immunofluorescence (mIF) Imaging: The system supports up to eight fluorescence-stained biomarkers simultaneously, allowing researchers to analyze large cohorts of samples with ease.
• Automation and High Throughput: Capable of scanning up to 100 slides in a single run, Axioscan 7 improves research throughput and ensures reproducible, high-quality results for longitudinal and multi-site studies.
• AI-powered Image Analysis: The system integrates AI-driven routines for automated scanning and image analysis, increasing productivity, reducing manual steps, and ensuring consistency in results.
• Advanced Reagents: Collaborating with Ultivue, ZEISS integrates OmniVUE™ reagents, offering DNA-based amplification technology for high specificity and dynamic range, enabling faster and more efficient data collection.
• Lab Automation: The solution includes a user-friendly workflow manager software and supports Laboratory Information Management System (LIMS) integration, allowing labs to streamline operations and adapt the system to their specific needs.

This advanced spatial biology solution is designed to enhance the scalability and reproducibility of spatial biology assays, making it an ideal choice for laboratories handling hundreds to thousands of samples per day. Available both as a standalone offering and an upgrade to existing ZEISS Axioscan 7 systems, the new system is poised to transform how spatial biology is conducted in clinical research.

About ZEISS

ZEISS is an internationally leading technology enterprise operating in the fields of optics and optoelectronics. In the previous fiscal year, the ZEISS Group generated annual revenue around 11 billion euros in its four segments Semiconductor Manufacturing Technology, Industrial Quality & Research, Medical Technology and Consumer Markets (30 September 2024).

For its customers, ZEISS develops, produces and distributes highly innovative solutions for industrial metrology and quality assurance, microscopy solutions for the life sciences and materials research, and medical technology solutions for diagnostics and treatment in ophthalmology and microsurgery. The name ZEISS is also synonymous with the world’s leading lithography optics, which are used by the chip industry to manufacture semiconductor components. There is global demand for trendsetting ZEISS brand products such as eyeglass lenses, camera lenses and binoculars.

With a portfolio aligned with future growth areas like digitalization, healthcare and Smart Production and a strong brand, ZEISS is shaping the future of technology and constantly advancing the world of optics and related fields with its solutions. The company’s significant, sustainable investments in research and development lay the foundation for the success and continued expansion of ZEISS’ technology and market leadership. ZEISS invests 15 percent of its revenue in research and development – this high level of expenditure has a long tradition at ZEISS and is also an investment in the future.

With over 46,000 employees, ZEISS is active globally in around 50 countries with more than 60 sales and service locations, around 40 research and development facilities, and 35 production facilities worldwide (30 September 2024). Founded in 1846 in Jena, the company is headquartered in Oberkochen, Germany. The Carl Zeiss Foundation, one of the largest foundations in Germany committed to the promotion of science, is the sole owner of the holding company, Carl Zeiss AG.

Further information at www.zeiss.com

ZEISS Research Microscopy Solutions

ZEISS Research Microscopy Solutions is the leading provider of light, electron, X-ray microscope systems, correlative microscopy and software solutions leveraging AI technologies. The portfolio comprises of products and services for life sciences, materials and industrial research, as well as education and clinical routine applications. The unit is headquartered in Jena. Additional production and development sites are located in Germany, UK, USA and China. ZEISS Research Microscopy Solutions is part of the Industrial Quality & Research segment.

Further information at www.zeiss.com/microscopy

Media Contact:

Vybhav Sinha
ZEISS Research Microscopy Solutions
Tel: +49 (0) 3641 64 3949
press.microscopy@zeiss.com

Source: ZEISS